SIB is an academic not-for-profit foundation established on March 30, 1998 whose mission is to promote research, the development of databanks and computer technologies, teaching and service activities in the field of bioinformatics, in Switzerland with international collaborations.
The Institute has three roles. They are: Teaching, Service and research.
- It maintains databases of SWISS-PROT, PROSITE, EPD, TrEST, TrGEN(predicted proteins) and etc.
- It create softwares of Deep view, Melanie, ESTScan, pftools and etc.
- It provides services and helpdesk for request tracking, publications and serveral web servers.
SIB also provide education for Bachelors, Masters and PhD courses. They also have courses at other countries.
- SIB also do research on new and improved algorithms, new technology, new tools and new databases. Research are done mostly on sequence and expression analysis, 3D structure, and proteomics, but also Systems Biology and Evolution.
The recent project happening at SIB is the Vital-IT.
Vital-IT
Vital-IT is an innovative life science informatics initiative providing computational resources, consultancy and training to connect fundamental and applied research. It represents an opportunity for European researchers to make use, free of charge, of Vital-IT's Integrated Computational Genomics Resources for projects in any of the life science field.
This project, through funding provided by the EU 6th framework Programme, started in 2006 and will continue until 2010. It consists of three module. They are: Training, Remote access and Visiting Developer.
Training
For Training, users, in particular those with limited technical experiences, can attend course on the technical aspects of the infrastructure, to learn how to take full advantage of it. The training mainly target new users from european countries. It is open to graduate students, post doctoral fellows, and more senior researchers. Part of the travel and living expenses can be provided for people attending the course as well.
Remote Access
Remote access to the Vital-IT infrastructure and computational genomics environment is provided via a new user-oriented Web interface. Successful applicants will be provided with a user account on Vital-IT and adequate CPU and disk storage quota to carry out the proposed project. This programme is primarily intended for projects that depend on database and software resources that were developed at Vital-IT and cannot easily be ported to another HPC centre. Requests for remote access to Vital-IT will also be evaluated by the review panel mentioned above. Remote users of the Vital-IT platform should prepare and submit their jobs according to detailed guidelines similar to those applied to existing users. These jobs should be able to run without requiring further assistance from Vital-IT personnel, and will partly be selected according to this criterion.
Visiting Developer
Visiting developers may stay for a period from one week to two months at Vital-IT, with a likely average of one month. Their activities may include the development of new software for HPC applications in life-science, parallelization and optimiziation of existing software for the specific hardware architecture of Vital-IT, and large data analysis projects making use of the rich database collection offered by this facility. They will be provided with office space, free access to all hardware and software resources required by the project, and technical assistance from Vital-IT staff. Visiting developers will be selected primarily on the basis of a project proposal that will be evaluated by a review panel including external experts in high performance computing, bioinformatics and genomics, including representatives from industry.
Vital-IT can be for institutions, companies or even individuals and the databases can either be local or public.
Link: http://www.vital-it.ch/
Another project of SIB is the "MyHits" which is dedicated to the annotation of protein sequences and to the analysis of their domains and signatures.
"MyHits provides full access to
- standard bioinformatics programs (e.g. PSI-BLAST, ClustalW, T-Coffee, Jalview)
- a large number of protein sequence databases including:
- standard databases, such as SwissProt, TrEMBL, etc.
- locally developed databases, such as TrEST, TrGEN, trome, splice variants, etc. - databases of protein motifs (Prosite, Interpro)
- a precomputed list of matches (‘hits’) between the sequence and motif databases. "
all these information can be found at: http://www.isb-sib.ch/projects/intro.htm
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