Proteomics is the large-scale study of proteins, particularly their structures and function. Proteins are vital parts of living organisms, as they are the main components of the physiological pathways of cells.
Proteomics is often considered the next step in the study of biological systems, after genomics. It is much more complicated than genomics, mostly because while an organism's genome is rather constant, a proteome differs from cell to cell and constantly changes through its biochemical interactions with the genome and the environment.
Recent projects on Proteomics
- HUPO Proteome Biology of Stem Cells Initiative
- Human Liver Proteome Project
- Proteomic Analysis of the Human Serum Proteome
This project was to show that the potential of proteomics among stem call which is charged with characterizing all of the known human embryonic stem call lines, have helped rally enthusiasm. Becauses of these results, stem cell researchers are starting to realize that proteomics approaches could shed light on important processes that are specific to stem cell.
Source: http://pubs.acs.org/subscribe/journals/jprobs/6/i09/html/0907proteomics.html
This project was to reveal the "solar systems" of the hu8man liver proteome, expression profiles, modification profiles, a protein linkage (protein-protein interaction) map, and a proteome localization map, and to define an ORFeome, physiome, and pathome. Setting up a management infrastructure, identified reference laboratories, confirmed standard operating procedures, initiated international research collaborations, and finally achieved the first set of expression profile data.
Source : http://www.mcponline.org/cgi/content/abstract/4/12/1841
This project was to establish the potential of the human serum proteome for screening and diagnosis in large populations using existing cutting-edge technologies for high-throughput protein analysis and biomarker discovery.
Source : http://gammerman.com/grants.htm
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